Hydrocodone or dihydroxycodeinone is a semi-synthetic opioid derived from natural opiates of codeine or thebaine. It was synthesized in Germany in 1920. Hydrocodone is an orally effective narcotic analgesic and an anti-cough agent. It is usually available in tablets, capsules, in the form of syrup, and is included in many medications. The drug acts as an analgesic and strong cough suppressant. Included in the list of drugs, trafficking in which is prohibited in the Russian Federation.
Hydrocodone 5-325mg reduces pain by binding to the opioid receptors of the brain and spinal cord. Drinking with alcohol can increase drowsiness. Interaction with monoamine oxidase inhibitors, as well as other drugs, can cause drowsiness. Use of the drug during pregnancy is prohibited, can lead to breathing problems and even miscarriage.
Side effects: dizziness, nausea, drowsiness, constipation, vomiting and euphoria. In rare cases, allergic reaction, blood supply disorders, changes in mood, mental nebula, anxiety, lethargy, difficulty urinating, cramps, rash.
The combination of hydrocodone with other drugs (such as paracetamol, aspirin, ibuprofen and chomatrophin, methyl bromide) is part of many medications.
The objectives of the combination are as follows:
- Provide an increase in anesthesia, by combining the effects of drugs;
- To limit the consumption of hydrocodone, causing unpleasant and often dangerous side effects in overdoses.
Consumption of hydrocodone should not exceed 40 mg in patients with susceptibility to opiates. A typical therapeutic range is 5-60 mg per day, in 4-6 doses of 2.5-10 mg. When administering combined agents with paracetamol (in some countries – acetaminophen / APAP), do not exceed 4000 mg of paracetamol per day. You can buy Hydrocodone online is USA-UK-Canada. ( mediattics.com )
In chronic pain patients, the dose is increased to 180 mg of hydrocodone per day (only in opioid dependent, to increase gradually, lethal for a new patient).
Signs of a pre-condition include difficulty breathing, extreme drowsiness, numbness, cold and / or sticky skin, sometimes bradycardia, hypotension, to whom.
Serious overdose can lead to cardiac arrest, death.
Mixing hydrocodone with alcohol, drugs, amphetamines, barbiturates can lead to serious adverse effects including cardiac arrest, heart attack, respiratory arrest, liver and / or kidney failure, jaundice, amnesia, blindness and coma.
Fatal consequences of use
Serious excess of therapeutic doses and long-term administration of the agent causes pathological changes in the body, which cause severe illnesses and even death.
spasm of respiratory organs and its stop;
multiple organ failure – the liver, kidneys stop working, which causes jaundice;
amnesia, loss of vision;
The most horrific consequences occur when combined with Vicodin and alcohol or other drugs.